Stem Cell Transplants: New Hope for Diabetics..!!

Scientists in University of British Columbia are able to reverse diabetes in mice by transplanting with human stem cells. Discovery that may be path breaking in finding a cure for a disease that affects almost every nation on planet.

  • Type 1 diabetes 
    • is a chronic disease that results from insufficient production of insulin from pancreatic β-cells.
    • Insulin, is a hormone that enables glucose to be stored by the body's muscle, fat and liver to be used as fuel. 
    • This Insulin shortage can lead to high blood sugar, heart attack, stroke, nerve damage and kidney failure etc. 
  • Most commonly used Treatment 
    • The most commonly type 1 diabetes is treated by regular injections of insulin. 
    • Islet cell replacement can effectively treat diabetes but is currently severely limited by the reliance upon cadaveric donor tissue.
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  • Study: 
    • Scientists led by Alireza Rezania et al, included researchers from Canada and New Jersey- used mice into which human stem cells were injected.
  • Result:
    • They were able to wean diabetic mice off of insulin four months after the rodents were transplanted with human pancreatic stem cells. 
    • The latest study shows again that human stem cell transplants can successfully restore insulin production and reverse type 1 diabetes in mice.
    • Additionally, Scientist found that the mice were able to maintain healthy blood sugar levels even after they were fed large quantities of sugar.
  • Previous research:
  • Future Prospects:
    • So...this finding support the feasibility of using Human Stem Cells as an alternative to cadaveric islets for treating patients with diabetes which will be a sigh of relief for so many people suffering from it.