Scientists in University of British Columbia are able to reverse diabetes in mice by transplanting with human stem cells. Discovery that may be path breaking in finding a cure for a disease that affects almost every nation on planet.
- Type 1 diabetes
- is a chronic disease that results from insufficient production of insulin from pancreatic β-cells.
- Insulin, is a hormone that enables glucose to be stored by the body's muscle, fat and liver to be used as fuel.
- This Insulin shortage can lead to high blood sugar, heart attack, stroke, nerve damage and kidney failure etc.
- Most commonly used Treatment
- The most commonly type 1 diabetes is treated by regular injections of insulin.
- Islet cell replacement can effectively treat diabetes but is currently severely limited by the reliance upon cadaveric donor tissue.
- Study:
- Scientists led by Alireza Rezania et al, included researchers from Canada and New Jersey- used mice into which human stem cells were injected.
- Result:
- They were able to wean diabetic mice off of insulin four months after the rodents were transplanted with human pancreatic stem cells.
- The latest study shows again that human stem cell transplants can successfully restore insulin production and reverse type 1 diabetes in mice.
- Additionally, Scientist found that the mice were able to maintain healthy blood sugar levels even after they were fed large quantities of sugar.
- Previous research:
- published in the Journal of the American Medical Association, also concluded that type 1 diabetes can be successfully reversed by injecting patients with their own stem cells.
- Future Prospects:
- So...this finding support the feasibility of using Human Stem Cells as an alternative to cadaveric islets for treating patients with diabetes which will be a sigh of relief for so many people suffering from it.